About Clinical Research and the Human Epilepsy Project

Our study coordinators and doctors are excited and motivated about finding a cure for epilepsy.

We want our participants to have a clear understanding about the HEP research study before they decide to participate. Patients under no circumstances will be forced to participate in the study and can change their mind at any time.

Patient-centered research

A patient during a yearly visit with DR manu HEgde M.D., Ph.D.

A patient during a yearly visit with DR manu HEgde M.D., Ph.D.

When a participant enrolls in the HEP study, they are matched with a study coordinator and a study doctor, who become that patient's Research Team. The study team will monitor the patient's epilepsy for at least three years and can often be a resource to help the newly diagnosed participant navigate the world of epilepsy care.

About Participating in the Human Epilepsy Project

If you answer yes to the three questions below, you may be eligible to participate:

  • Did you start treatment for focal epilepsy in the past 4 months?
  • Have you had 2 or more seizures in the past year?
  • Are you between the ages of 12-60 years old?

More detailed Inclusion/Exclusion criteria.

For assistance with deciding if you are eligible, contact us to express an interest in participating in HEP.

What will I need to do if I participate?

HEP participants are followed for three years. Participating takes a few hours at first and then about an hour per year. The big study visit is at enrollment where participants answer questions about their epilepsy, take some online tests, give blood and urine samples, have an MRI and EEG, and receive an iPod Touch with seizure tracking software. After the initial visit there are three consecutive annual checkups performed at the end of each year.

A patient is being examined by DR manu HEgde M.D., Ph.D. at UCSF San francisco, CA during a yearly visit

A patient is being examined by DR manu HEgde M.D., Ph.D. at UCSF San francisco, CA during a yearly visit

 

What is a medical research study like the Human Epilepsy Project?

Medical research is conducted to aid the body of knowledge in the field of medicine. This can be divided into two general categories: new treatments that are tested in clinical trials, and all other research contributing to the development of new treatments. HEP is a biomarkers research study, and there is no treatment that is being tested. Therefore, we are not a clinical trial. HEP investigators will be looking for patterns in DNA, proteins, MRI, and EEG, and other biomarkers that explain the development of focal epilepsy.

Here are some general questions to think about when you consider joining HEP:

 

The decision to participate in medical research is a very personal one. However, there are guidelines to protect study participants. Research in humans is permitted only in volunteers who have been briefed about both the potential benefits and hazards of trial participation. This is called informed consent. It is the responsibility of the research team to explain the risks to potential study participants.

For more information

Understanding Clinical Trials - An Introduction to Clinical Trials provided by the National Institutes of Health.