What is the Human Epilepsy Project?

HEP is an international team of over 300 doctors, researchers, healthcare workers and patients working together at 27 hospitals, to study the biomarkers of new-onset focal epilepsy . Together, we are working toward the day when any patient can come to their doctor and immediately get an appropriate treatment that cures their seizures.


The doctors of HEP study pictures of the brain and look for molecules and genes to help understand how patients respond to treatments and become seizure-free. As a result of this research future patients with epilepsy will be able to receive an individualized treatment plan, resulting in a more immediate improvement or cure for their condition. Information gathered from the studies may also aid the development of medicines that will prevent epilepsy.

Who can participate?


The Human Epilepsy project is looking for two kinds of patients:

New onset patients who:

  • Have a history of focal epilepsy
  • Have had at least two confirmed spontaneous seizures at least 24 hours apart, or one seizure with an abnormal EEG or MRI, in the past 12 months
  • Began epilepsy medicine within the past 4 months

Treatment resistant patients who:

  • Have a history of focal epilepsy
  • Have four or more seizures per month
  • Have tried four or more drugs to control seizures without success

HEP Funding

HEP is funded by the Epilepsy Study Consortium, a nonprofit organization comprised of epilepsy doctors, working to improve the care of people with epilepsy by funding and managing research projects.